Description

1,5-Cyclohexadiene-1-Carboxylicacid,3-Amino-,(-)-(9Ci) is a chiral, functionalized cyclohexadiene derivative of significant interest in advanced organic synthesis. This compound matters as a versatile, optically active building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and specialty chemical industries for applications such as asymmetric synthesis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates requiring specific stereochemistry.
• Asymmetric Synthesis: Utilized as a building block in catalytic asymmetric reactions to introduce the (-)-enantiomer of the 3-amino-1,5-cyclohexadiene-1-carboxylic acid scaffold into target molecules.
• Agrochemical Research: Employed in the synthesis of advanced intermediates for new herbicides, fungicides, or plant growth regulators where the chiral diene structure imparts specific biological activity.
• Ligand and Catalyst Development: Acts as a precursor for the synthesis of novel chiral ligands or organocatalysts used in enantioselective transformations.
• Material Science Research: Investigated as a monomer or functional component in the development of specialized polymers with unique optical or electronic properties.
• Academic & Institutional Research: Used in universities and research institutes for methodological studies in organic chemistry and the exploration of new synthetic pathways.

Basic Information

Product Name	1,5-Cyclohexadiene-1-Carboxylicacid,3-Amino-,(-)-(9Ci)
CAS No.	70249-37-5
Molecular Formula	C7H9NO2
Molecular Weight	139.15 g/mol
Synonyms	(-)-3-Amino-1,5-cyclohexadiene-1-carboxylic acid; (1R,3S)-3-Amino-1,5-cyclohexadiene-1-carboxylic acid; 3-Amino-1,5-cyclohexadiene-1-carboxylic acid, (-)-; 1,5-Cyclohexadiene-1-carboxylic acid, 3-amino-, (-)-; 70249-37-5; (1R,3S)-3-Amino-cyclohexa-1,5-diene-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1,5-Cyclohexadiene-1-Carboxylicacid,3-Amino-,(-)-(9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and potential degradation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.