Description

4,4-Diethoxybutan-1-Ol is a versatile chemical intermediate characterized by its acetal-protected aldehyde functionality and terminal hydroxyl group. This bifunctional nature makes it a valuable building block for the synthesis of more complex molecules in fine chemical and pharmaceutical manufacturing. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing heterocycles, chiral ligands, and polymer precursors.

Application

• Pharmaceutical Intermediate: Key synthon for the production of active pharmaceutical ingredients (APIs), particularly in the synthesis of pyrrolidines and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators requiring specific acetal-protected aldehyde chemistry.
• Polymer Chemistry: Serves as a monomer or chain extender in the production of specialty polyesters and polyurethanes, contributing to tailored material properties.
• Flavor and Fragrance Industry: Employed in the synthesis of aroma chemicals and flavoring agents that benefit from its masked carbonyl group.
• Organic Synthesis Reagent: A useful precursor in multi-step synthetic routes for the controlled introduction of butane-1,4-diol equivalents under mild conditions.
• Crosslinking Agent: Functions in formulations for coatings, adhesives, and resins where its dual functionality can promote network formation.

Basic Information

Product Name	4,4-Diethoxybutan-1-Ol
CAS No.	70216-75-0
Molecular Formula	C8H18O3
Molecular Weight	162.23 g/mol
Synonyms	1,1-Diethoxy-4-hydroxybutane; 4-Hydroxybutyraldehyde Diethyl Acetal; Butane-1,1,4-triol Diethyl Acetal; 4-Hydroxybutanal Diethyl Acetal; 4,4-Diethoxy-1-butanol; 1-Butanol, 4,4-diethoxy-; 4-Hydroxybutyraldehyde Diethyl Acetal
EINECS	Contact for details

Quality Control

Our 4,4-Diethoxybutan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.420 - 1.430
Density (20°C)	0.95 - 0.98 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.