Description

Ethyl 7-Chloro-1-Ethyl-6-Nitro-4-Oxo-1,4-Dihydro-3-Quinolinecarboxylate is a high-purity, synthetically valuable quinoline derivative. This compound serves as a critical advanced intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class. It is essential for research and manufacturing organizations in the pharmaceutical and fine chemical sectors seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of fluoroquinolone antibacterial agents.
• Research & Development: Used in medicinal chemistry for the design and discovery of new quinolone-based therapeutic molecules.
• Fine Chemical Synthesis: Employed as a specialized building block for constructing complex heterocyclic compounds in custom synthesis projects.
• API Manufacturing: Integrated into Good Manufacturing Practice (GMP) production processes for target active pharmaceutical ingredients.

Basic Information

Product Name	Ethyl 7-Chloro-1-Ethyl-6-Nitro-4-Oxo-1,4-Dihydro-3-Quinolinecarboxylate
CAS No.	70186-33-3
Molecular Formula	C₁₄H₁₃ClN₂O₅
Molecular Weight	324.72 g/mol
Synonyms	7-Chloro-1-ethyl-6-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester; Ethyl 7-chloro-1-ethyl-6-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1,4-Dihydro-7-chloro-1-ethyl-6-nitro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 1,4-dihydro-7-chloro-1-ethyl-6-nitro-4-oxo-, ethyl ester; Intermediate for fluoroquinolone synthesis
EINECS	Contact for details

Quality Control

Our Ethyl 7-Chloro-1-Ethyl-6-Nitro-4-Oxo-1,4-Dihydro-3-Quinolinecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.