Description

1-(3-Chlorobenzylidene)-5-Methoxy-2-Methyl-1H-Indene-3-Acetic Acid is a high-purity synthetic indene derivative with significant potential as a key pharmaceutical intermediate. This compound is valued for its specific molecular architecture, which serves as a crucial building block in advanced organic synthesis. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the research and synthesis of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting inflammation or central nervous system disorders.
• Organic Synthesis Building Block: Utilized in complex multi-step synthesis for constructing fused ring systems, leveraging its reactive indene-acetic acid core for further functionalization.
• Medicinal Chemistry Research: Employed in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization due to its modifiable chlorobenzylidene and methoxy substituents.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, dyes, and advanced materials where its specific aromatic and olefinic character is required.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	1-(3-Chlorobenzylidene)-5-Methoxy-2-Methyl-1H-Indene-3-Acetic Acid
CAS No.	70172-34-8
Molecular Formula	C20H17ClO3
Molecular Weight	340.80 g/mol
Synonyms	1-[(3-Chlorophenyl)methylene]-5-methoxy-2-methyl-1H-indene-3-acetic acid; 5-Methoxy-2-methyl-1-(3-chlorobenzylidene)indene-3-acetic acid; 1-(3-Chlorobenzylidene)-5-methoxy-2-methylindene-3-acetic acid; Indene-3-acetic acid, 1-(3-chlorobenzylidene)-5-methoxy-2-methyl-; 70172-34-8; (E)-1-(3-Chlorobenzylidene)-5-methoxy-2-methyl-1H-indene-3-acetic acid; (Z)-1-(3-Chlorobenzylidene)-5-methoxy-2-methyl-1H-indene-3-acetic acid
EINECS	Contact for details

Quality Control

Our 1-(3-Chlorobenzylidene)-5-Methoxy-2-Methyl-1H-Indene-3-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.