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n-(4-Azido-2-Nitrophenyl)Glycyl Hydrazide CAS NO 70170-74-0


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CAS No.:70170-74-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-(4-Azido-2-Nitrophenyl)Glycyl Hydrazide is a specialized heterobifunctional chemical reagent featuring both a photoreactive aryl azide group and a hydrazide moiety. This compound is valued for its ability to act as a photoactivatable crosslinker, enabling the formation of covalent bonds upon exposure to UV or visible light. It is primarily utilized by researchers and manufacturers in the fields of bioconjugation, materials science, and pharmaceutical development for labeling, surface modification, and the creation of novel polymer networks.

Application

  • Bioconjugation and Protein Labeling: Used as a photo-crosslinker to attach probes, tags, or other molecules to proteins, antibodies, or peptides under mild conditions.
  • Surface Functionalization: Employed to modify the surface properties of polymers, nanoparticles, or chips by introducing reactive hydrazide groups for further coupling.
  • Polymer Chemistry: Serves as a crosslinking agent or monomer in the synthesis of light-responsive hydrogels and smart polymeric materials.
  • Affinity Chromatography: Facilitates the immobilization of ligands onto solid supports for the purification of specific biomolecules.
  • Diagnostic Assay Development: Integral in creating stable conjugates for immunoassays, biosensors, and other diagnostic platforms.
  • Chemical Biology Research: A key tool for studying protein-protein interactions, mapping binding sites, and developing targeted drug delivery systems.

Basic Information

Product Name n-(4-Azido-2-Nitrophenyl)Glycyl Hydrazide
CAS No. 70170-74-0
Molecular Formula C8H8N6O3
Molecular Weight 236.19 g/mol
Synonyms 4-Azido-2-nitrobenzoyl glycine hydrazide; Glycine, N-[(4-azido-2-nitrophenyl)carbonyl]-, hydrazide; ANP-Gly-Hz; 4-Azido-2-nitrohippuryl hydrazide; N-(4-Azido-2-nitrobenzoyl)glycine hydrazide; N-(4-Azido-2-nitrophenyl)glycine hydrazide; 2-[(4-Azido-2-nitrobenzoyl)amino]acetohydrazide
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Quality Control

Our n-(4-Azido-2-Nitrophenyl)Glycyl Hydrazide is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere for long-term stability. This compound is strictly light-sensitive and must be handled under subdued lighting conditions to prevent premature decomposition. Allow the container to reach room temperature in the dark before opening to minimize condensation.

Specification

Item Specification
Appearance Yellow to orange crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Solubility Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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