Description

(2R)-1,4α,4Aα,7α-Tetramethyl-3α,6α-Dibromo-7-Chloro-3,4,4A,5,6,7,8,9-Octahydro-2H-Benzocycloheptene-2β-Ol is a high-purity, stereochemically defined synthetic intermediate characterized by its complex polycyclic structure and halogen substituents. This compound is critical for advanced organic synthesis, particularly in the development of novel pharmacologically active molecules and specialty fine chemicals. It is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) or anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its halogenated structure for potential biological activity.
• Chemical Synthesis Reagent: Acts as a versatile precursor for further functionalization (e.g., cross-coupling reactions, dehalogenation, oxidation) in complex molecule assembly.
• Material Science Precursor: Potential use in synthesizing specialty monomers or ligands for catalysts and advanced polymeric materials.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including stereoselective synthesis and halogen chemistry research.

Basic Information

Product Name	(2R)-1,4α,4Aα,7α-Tetramethyl-3α,6α-Dibromo-7-Chloro-3,4,4A,5,6,7,8,9-Octahydro-2H-Benzocycloheptene-2β-Ol
CAS No.	70073-12-0
Molecular Formula	C15H23Br2ClO
Molecular Weight	438.61 g/mol
Synonyms	(2R)-3α,6α-Dibromo-7-chloro-1,4α,4aα,7α-tetramethyl-2β-ol-decahydrobenzocycloheptene; 3α,6α-Dibromo-7-chloro-1,4α,4aα,7α-tetramethyl-2β-ol-perhydrobenzocycloheptene; 2H-Benzocyclohepten-2-ol, 3,4,4a,5,6,7,8,9-octahydro-3,6-dibromo-7-chloro-1,4,4a,7-tetramethyl-, (2R,3S,4aS,6S,7S,9aS)-; Halogenated Benzocycloheptene Derivative; Dibromo-Chloro Tetramethyl Benzocycloheptenol
EINECS	Contact for details

Quality Control

Our production of (2R)-1,4α,4Aα,7α-Tetramethyl-3α,6α-Dibromo-7-Chloro-3,4,4A,5,6,7,8,9-Octahydro-2H-Benzocycloheptene-2β-Ol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and stereochemical composition are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and prolonged exposure to air; it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.