Description

3-Bromo-[1,1-Biphenyl]-4-Ol is a high-purity brominated biphenyl derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a phenolic hydroxyl group, makes it an essential intermediate for constructing complex molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and inflammation.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its biphenyl core for enhanced biological activity.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized phosphine or N-heterocyclic carbene (NHC) ligands used in cross-coupling catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where the biphenyl unit contributes to desired electronic and structural properties.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in regulatory and research laboratories.

Basic Information

Product Name	3-Bromo-[1,1-Biphenyl]-4-Ol
CAS No.	70066-67-0
Molecular Formula	C₁₂H₉BrO
Molecular Weight	249.10 g/mol
Synonyms	3-Bromo-4-hydroxybiphenyl; 4-Hydroxy-3-phenylbromobenzene; 3-Bromo-4-phenylphenol; (3-Bromo-4-hydroxyphenyl)benzene; Biphenyl-4-ol, 3-bromo-; 3-Bromobiphenyl-4-ol; 4'-Hydroxy-3'-bromobiphenyl
EINECS	Contact for details

Quality Control

Our 3-Bromo-[1,1-Biphenyl]-4-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation by FT-IR and NMR, and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch, detailing all specifications and test results. Our quality protocols are designed to meet the stringent requirements of cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.