Description

1,3-Dichloroisoquinoline is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its dual reactive sites, which enable selective functionalization for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of bioactive isoquinoline derivatives and potential drug candidates.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides due to its reactive halogen substituents.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting compounds.
• Cross-Coupling Reactions: An effective substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination.
• Nucleophilic Aromatic Substitution: The chlorine atoms are amenable to displacement by various nucleophiles, enabling diverse derivatization.

Basic Information

Product Name	1,3-Dichloroisoquinoline
CAS No.	7742-73-6
Molecular Formula	C9H5Cl2N
Molecular Weight	198.05 g/mol
Synonyms	1,3-Dichloro-2-azanaphthalene; Isoquinoline, 1,3-dichloro-; 1,3-Dichloroisoquinoline; 1,3-DCIQ; 1,3-Dichloro-isoquinoline; 1,3-Dichloro-2-azaanthracene (obsolete); NSC 406122
EINECS	Contact for details

Quality Control

Our 1,3-Dichloroisoquinoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.