Description

1-Acetamido-Acetone is a versatile organic compound featuring both ketone and amide functional groups, making it a valuable building block in synthetic chemistry. Its bifunctional nature allows for selective reactions, enabling the efficient synthesis of complex heterocyclic structures and fine chemicals. This intermediate is particularly sought after by the pharmaceutical, agrochemical, and specialty chemical industries for research and development as well as process-scale manufacturing.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), including potential candidates for neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Heterocyclic Chemistry: Essential building block for constructing nitrogen-containing heterocycles like pyrroles, pyrazoles, and imidazoles, which are core structures in many bioactive molecules.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and advanced materials requiring specific ketone-amide functionalities.
• Bioconjugation & Linker Chemistry: Useful in biochemical research for modifying proteins or creating cleavable linkers due to its reactive carbonyl group.
• Academic & Industrial R&D: Serves as a critical reagent in method development and exploratory synthesis within organic chemistry laboratories.

Basic Information

Product Name	1-Acetamido-Acetone
CAS No.	7737-16-8
Molecular Formula	C5H9NO2
Molecular Weight	115.13 g/mol
Synonyms	N-Acetyl-2-aminoacetone; 3-Oxobutanamide; Acetoneacetamide; 1-Acetylaminoacetone; 3-Oxo-N-acetylpropylamine; Acetylaminopropanone; 2-Propanone, 1-(acetylamino)-; Butanamide, 3-oxo-
EINECS	231-800-6

Quality Control

Our 1-Acetamido-Acetone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.