Description

Coumarin-6-Carboxylic Acid is a versatile and high-purity organic compound that serves as a critical building block and fluorescent probe in advanced chemical synthesis. Its value lies in its functionalized coumarin core, which provides a reactive carboxylic acid group for derivatization and inherent fluorescence properties for detection and imaging. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients, sensors, and functional dyes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes or requiring fluorescent tagging for biological studies.
• Fluorescent Probe & Sensor Development: Utilized as a core structure for creating sensitive fluorescent probes and chemosensors for detecting metal ions, pH changes, or biological molecules.
• Agrochemical Research: Serves as a building block for developing new active ingredients with enhanced properties for crop protection.
• Organic Light-Emitting Diodes (OLEDs): Used in the research and development of emissive materials and electron-transport layers for display and lighting technologies.
• Dye & Pigment Synthesis: Acts as an intermediate for manufacturing advanced fluorescent dyes and pigments used in textiles, inks, and coatings.
• Bioconjugation & Labeling: The carboxylic acid group enables covalent attachment to proteins, antibodies, or nanoparticles for bioimaging and diagnostic applications.
• Academic & Industrial R&D: A fundamental reagent in organic chemistry laboratories for method development and exploring new coumarin-based chemistries.

Basic Information

Product Name	Coumarin-6-Carboxylic Acid
CAS No.	7734-80-7
Molecular Formula	C10H6O4
Molecular Weight	190.15 g/mol
Synonyms	6-Carboxycoumarin; Coumarin-6-carboxylic acid; 2-Oxo-2H-chromene-6-carboxylic acid; 2H-1-Benzopyran-2-one, 6-carboxy-; 6-Coumarincarboxylic acid; 6-Carboxy-2H-chromen-2-one; 2H-Chromen-2-one, 6-carboxy-; 6-Coumaric acid lactone carboxylic acid
EINECS	231-800-6

Quality Control

Our Coumarin-6-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for identity confirmation, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	255 - 260 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.