Description

1,4-Anhydro-D-Mannitol is a high-purity, versatile chemical intermediate derived from D-mannitol. This compound matters for its role as a key chiral building block in the synthesis of complex molecules, offering precise stereochemical control. It is primarily needed by the pharmaceutical industry for active pharmaceutical ingredient (API) development and by research institutions for advanced biochemical studies.

Application

• Pharmaceutical Synthesis: Serves as a crucial chiral precursor and scaffold in the development of novel active pharmaceutical ingredients (APIs) and prodrugs.
• Biochemical Research: Used as a standard or reagent in carbohydrate chemistry research, enzymatic studies, and metabolic pathway analysis.
• Cosmetic & Personal Care: Functions as a humectant and moisturizing agent in high-end skincare formulations due to its polyol structure.
• Food & Beverage Additives: Potential use as a low-calorie sweetener or texturizing agent in specialized food products.
• Industrial Chemical Intermediate: Acts as a starting material for the production of surfactants, plasticizers, and other specialty chemicals.
• Analytical Standards: Employed as a certified reference material (CRM) for quality control and method validation in analytical laboratories.

Basic Information

Item	Details
Product Name	1,4-Anhydro-D-Mannitol
CAS No.	7726-97-8
Molecular Formula	C6H12O5
Molecular Weight	164.16 g/mol
Synonyms	1,4-Anhydro-D-mannitol; D-1,4-Anhydromannitol; Isomannide; D-Isomannide; (3R,3aR,6R,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diol; 1,4:3,6-Dianhydro-D-mannitol; Dianhydromannitol
EINECS	231-782-4

Quality Control

Our 1,4-Anhydro-D-Mannitol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Rotation [α]20/D	Contact for details
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.