Description

(1S,5α)-4β-Methyl-1-Isopropylbicyclo[3.1.0]Hexan-3α-Ol is a high-purity, synthetically derived bicyclic tertiary alcohol with a complex, rigid molecular architecture. This compound matters as a versatile and valuable chiral building block and intermediate in advanced organic synthesis, offering a unique spatial configuration that is critical for imparting specific stereochemical properties to target molecules. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from asymmetric catalysis to the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly where the bicyclo[3.1.0]hexane scaffold is desired for its conformational rigidity.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where its specific stereochemistry can influence biological activity and selectivity.
• Asymmetric Catalysis Ligand Precursor: Acts as a starting material for the synthesis of sophisticated chiral ligands used in enantioselective catalytic processes.
• Fragrance and Flavor Chemistry: Employed in the synthesis of complex odorants and flavor compounds that require specific isopropyl and tertiary alcohol functionalities within a constrained ring system.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with unique thermal and mechanical properties derived from its strained bicyclic core.
• Academic and R&D Laboratories: Utilized as a reference standard or a challenging substrate in methodological studies and educational settings focused on stereochemistry and complex molecule synthesis.

Basic Information

Product Name	(1S,5α)-4β-Methyl-1-Isopropylbicyclo[3.1.0]Hexan-3α-Ol
CAS No.	7712-79-0
Molecular Formula	C10H18O
Molecular Weight	154.25 g/mol
Synonyms	4β-Methyl-1α-isopropylbicyclo[3.1.0]hexan-3α-ol; (1S,5α)-4β-Methyl-1-(1-methylethyl)bicyclo[3.1.0]hexan-3α-ol; 3α-Hydroxy-4β-methyl-1α-isopropylbicyclo[3.1.0]hexane; endo-4-Methyl-1-isopropylbicyclo[3.1.0]hexan-3-ol; Bicyclo[3.1.0]hexan-3-ol, 4-methyl-1-(1-methylethyl)-, (1S,5α,3α,4β)-; Chiral bicyclic alcohol intermediate
EINECS	Contact for details

Quality Control

Our (1S,5α)-4β-Methyl-1-Isopropylbicyclo[3.1.0]Hexan-3α-Ol is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and impurity profile is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.