Description

4-Chloro-1,5-Naphthyridine is a versatile halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its ability to act as a key precursor for the development of complex pharmacologically active molecules and functional materials. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial scaffold in the synthesis of potential drug candidates, particularly for kinase inhibitors, antiviral agents, and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the naphthyridine core.
• Material Science Precursor: Acts as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce the 1,5-naphthyridine moiety into more complex systems.
• Academic & R&D: Utilized in university and institutional laboratories for methodological studies and the exploration of new chemical reactions involving chlorinated nitrogen heterocycles.

Basic Information

Product Name	4-Chloro-1,5-Naphthyridine
CAS No.	7689-63-6
Molecular Formula	C8H5ClN2
Molecular Weight	164.59 g/mol
Synonyms	4-Chloro-1,5-naphthyridine; 1,5-Naphthyridine, 4-chloro-; 4-Chloro-1,5-diazanaphthalene; 4-Chloro-1,5-naphthyridine; 4-Chloro-1,5-naphthyridine (CAS 7689-63-6); 4-Chloro-1,5-naphthyridine, 98+%; 4-Chloro-1,5-naphthyridine, 95%
EINECS	Contact for details

Quality Control

Our 4-Chloro-1,5-Naphthyridine is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.