Description

2-Phenylquinazoline-4-Carboxylic Acid is a versatile heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique quinazoline core fused with a phenyl substituent makes it a valuable intermediate for creating complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinazoline-based drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new herbicides, fungicides, and plant growth regulators that leverage the bioactive quinazoline scaffold.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Acts as a versatile building block for constructing more complex heterocyclic compounds in medicinal and combinatorial chemistry.
• Academic & R&D: Employed in universities and corporate R&D labs for fundamental studies on heterocyclic chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	2-Phenylquinazoline-4-Carboxylic Acid
CAS No.	7672-01-7
Molecular Formula	C15H10N2O2
Molecular Weight	250.25 g/mol
Synonyms	4-Quinazolinecarboxylic acid, 2-phenyl-; 2-Phenyl-4-quinazolinecarboxylic acid; 2-Phenylquinazoline-4-carboxylic acid; NSC 403697; 2-Phenyl-1,3-diazanaphthalene-4-carboxylic acid; Quinazoline-4-carboxylic acid, 2-phenyl-; 2-Phenyl-4-carboxyquinazoline
EINECS	Contact for details

Quality Control

Our 2-Phenylquinazoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.