Description

3-(2-Amino-1-Hydroxypropyl)Phenol is a versatile organic compound featuring both phenolic and amino-alcohol functional groups, making it a valuable chiral building block and intermediate in advanced synthesis. Its molecular structure is critical for creating complex molecules with specific biological activity and stereochemical purity. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of β-adrenergic blocking agents (β-blockers) and other cardiovascular or neurological drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Fine Chemical Building Block: Serves as a precursor for ligands, catalysts, and complex organic molecules in asymmetric synthesis.
• Biochemical Research: Employed in studies of enzyme inhibition, receptor binding, and the development of diagnostic agents.
• Material Science: Potential monomer or cross-linking agent for the development of specialty polymers and resins.

Basic Information

Product Name	3-(2-Amino-1-Hydroxypropyl)Phenol
CAS No.	7619-17-2
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	1-(3-Hydroxyphenyl)-2-aminopropan-1-ol; 3-(1-Hydroxy-2-aminopropyl)phenol; DL-Octopamine (base); Norphenylephrine; α-(Aminomethyl)-3-hydroxybenzyl alcohol; 3-Hydroxy-α-((methylamino)methyl)benzyl alcohol; (±)-Octopamine; DL-p-Octopamine
EINECS	Contact for details

Quality Control

Our 3-(2-Amino-1-Hydroxypropyl)Phenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We support compliance with cGMP, ICH guidelines, and relevant pharmacopeial standards (USP/EP) for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation and absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Specific enantiomer available)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.