Description

3-Phenylazetidine Hydrochloride is a valuable nitrogen-containing heterocyclic building block, specifically an azetidine derivative. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its constrained four-membered ring structure, which can impart unique conformational and metabolic properties to target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the azetidine scaffold can contribute to improved biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced polymers and functional organic materials with specific optical or electronic properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Phenylazetidine Hydrochloride
CAS No.	7606-30-6
Molecular Formula	C9H12ClN
Molecular Weight	169.65 g/mol
Synonyms	3-Phenylazetidine HCl; 3-Phenylazetidine hydrochloride; Azetidine, 3-phenyl-, hydrochloride; 1-Azabicyclo[1.1.0]butane, 3-phenyl-, hydrochloride; Phenylazetidine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Phenylazetidine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from techniques such as HPLC, NMR, and mass spectrometry. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.