Description

(8α,9R)-6'-Methoxycinchonan-9-Ol/Hydrochloric Acid,(1:X) is a high-purity alkaloid salt derived from cinchona, serving as a critical chiral intermediate and resolving agent. Its value lies in enabling precise stereochemical control in asymmetric synthesis, a cornerstone of modern pharmaceutical development. This compound is essential for research laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical sectors requiring enantiomerically pure products.

Application

• As a chiral resolving agent for the separation of racemic mixtures of carboxylic acids and other acidic compounds.
• As a key intermediate in asymmetric synthesis for the production of enantiomerically pure pharmaceuticals.
• In the research and development of new catalytic systems and chiral ligands.
• For use as a reference standard in analytical method development and quality control (QC) laboratories.
• In the synthesis of specialty chemicals and advanced materials where chirality is a functional requirement.
• As a precursor in the preparation of other cinchona alkaloid derivatives with specific biological activity.

Basic Information

Product Name	(8α,9R)-6'-Methoxycinchonan-9-Ol/Hydrochloric Acid,(1:X)
CAS No.	7549-43-1
Molecular Formula	C20H25ClN2O2 • xHCl
Molecular Weight	360.88 (base) + x(36.46) g/mol
Synonyms	Cinchonan-9-ol, 6'-methoxy-, hydrochloride, (8α,9R)-; 6'-Methoxycinchonan-9-ol Hydrochloride; (8α,9R)-6'-Methoxycinchonan-9-ol Hydrochloride; Cinchonidine, 6'-methoxy-, hydrochloride; Hydroquinidine Hydrochloride; Hydrocinchonidine Hydrochloride; (8α,9R)-9-Hydroxy-6'-methoxycinchonan Hydrochloride
EINECS	Contact for details

Quality Control

Our (8α,9R)-6'-Methoxycinchonan-9-Ol/Hydrochloric Acid,(1:X) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical intermediates and research chemicals. A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.