Description

β-D-Glucopyranose, 1-Thio- is a thioglycoside derivative of glucose, where the oxygen atom in the anomeric position is replaced by sulfur. This structural modification imparts unique chemical properties, making it a valuable intermediate for the synthesis of more complex sulfur-containing carbohydrates and glycoconjugates. It is primarily utilized by research institutions and pharmaceutical companies engaged in carbohydrate chemistry, medicinal chemistry, and the development of enzyme inhibitors or diagnostic probes.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing thioglycoside-based prodrugs, enzyme inhibitors, and antiviral or anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for glycosidases and glycosyltransferases.
• Glycoconjugate Synthesis: Serves as a precursor for creating neoglycoproteins, glycolipids, and other labeled carbohydrate probes for biological studies.
• Chemical Biology Tool: Employed in the development of activity-based probes and metabolic labeling agents to study carbohydrate-related processes in cells.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	β-D-Glucopyranose, 1-Thio-
CAS No.	7534-35-2
Molecular Formula	C6H12O5S
Molecular Weight	196.22 g/mol
Synonyms	1-Thio-β-D-glucopyranose; 1-Thio-β-D-glucose; β-D-Glucopyranosyl mercaptan; 1-S-Glucose; 1-Thioglucose; Thioglucopyranose; 1-Deoxy-1-mercapto-β-D-glucopyranose; 1-Thio-D-glucose
EINECS	231-400-8

Quality Control

Our β-D-Glucopyranose, 1-Thio- is produced under a rigorous quality management system. Each batch is subjected to comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of related substances, to ensure it meets high-purity research-grade standards. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.