Description

2-Cyano-2-Methylpropanamide is a versatile cyanoacetamide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both a reactive cyano group and an amide moiety, enabling its use in the construction of complex heterocycles and pharmaceutical intermediates. This high-purity compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality raw materials for their synthetic pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing pyrimidine or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators where its cyano group is incorporated into the final active molecule.
• Organic Synthesis Building Block: Employed in Knoevenagel condensations and other C-C bond-forming reactions to create α,β-unsaturated nitriles and other advanced intermediates.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers, including polyamides and resins with specific thermal or chemical resistance properties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and novel compound libraries.
• Dye and Pigment Industry: Intermediate in the synthesis of certain organic dyes and colorants, leveraging the reactivity of the cyano group.

Basic Information

Product Name	2-Cyano-2-Methylpropanamide
CAS No.	7505-93-3
Molecular Formula	C5H8N2O
Molecular Weight	112.13 g/mol
Synonyms	2-Cyano-2-methylpropionamide; 2-Methyl-2-cyanopropanamide; 2-Methylmalonamide mononitrile; α-Cyano-isobutyramide; Isobutyronitrile, α-cyano-; NSC 163063; 2-Cyano-2-methylpropanamide; Cyanomethylisobutyramide
EINECS	Contact for details

Quality Control

Our 2-Cyano-2-Methylpropanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.