Description

2-Chloro-2-Phenylacetamide is a versatile halogenated aromatic amide building block of significant interest in synthetic organic chemistry. Its value lies in its bifunctional structure, featuring both a reactive chloroacetyl group and a phenyl ring, making it a key intermediate for constructing more complex molecules. This compound is primarily needed by research and development laboratories, pharmaceutical manufacturers, and agrochemical companies for the synthesis of active pharmaceutical ingredients (APIs), fine chemicals, and specialized materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a phenylacetamide or chloroacetamide pharmacophore.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents where its halogenated structure imparts biological activity.
• Organic Synthesis Building Block: Serves as a versatile reagent for nucleophilic substitution reactions, amide bond formation, and as a scaffold for constructing heterocyclic compounds in academic and industrial R&D.
• Material Science Research: Investigated as a monomer or modifying agent in the development of specialized polymers and advanced materials with tailored properties.
• Biochemical Research: Potential use in the synthesis of enzyme inhibitors or probes for studying biological pathways and mechanisms.

Basic Information

Product Name	2-Chloro-2-Phenylacetamide
CAS No.	7462-76-2
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	α-Chloro-α-phenylacetamide; 2-Chloro-2-phenylacetamide; NSC 403697; Phenylchloroacetamide; (Chloro)(phenyl)acetamide; α-Chlorophenylacetamide; Chloro(phenyl)acetamide; 2-Phenyl-2-chloroacetamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-2-Phenylacetamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.