Description

2-Chloroquinolin-8-Amine is a versatile halogenated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amine and a chlorine substituent on the quinoline core, makes it a valuable intermediate for constructing complex molecules with targeted biological and material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting infectious diseases, cancer, and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides, leveraging the bioactive quinoline scaffold.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized quinoline-based dyes and colorants.
• Ligand for Catalysis: Utilized to synthesize complex ligands for transition metal catalysts used in cross-coupling and other organic transformations.
• Academic & R&D: A fundamental reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	2-Chloroquinolin-8-Amine
CAS No.	7461-11-2
Molecular Formula	C9H7ClN2
Molecular Weight	178.62 g/mol
Synonyms	8-Amino-2-chloroquinoline; 2-Chloro-8-quinolinamine; 2-Chloro-8-aminoquinoline; 8-Quinolinamine, 2-chloro-; 2-Chlor-8-aminochinolin; 2-Cl-8-NH2-Q
EINECS	Contact for details

Quality Control

Every batch of 2-Chloroquinolin-8-Amine is produced and tested under a strict quality management system. We ensure high purity and consistency through comprehensive analytical techniques including HPLC, GC, and NMR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.