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4(3H)-Quinazolinone, 2-(4-Chlorophenyl)- CAS NO 7455-77-8


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CAS No.:7455-77-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4(3H)-Quinazolinone, 2-(4-Chlorophenyl)- is a high-purity organic compound belonging to the quinazolinone class, a scaffold of significant interest in medicinal chemistry. Its core value lies in its role as a versatile and critical pharmaceutical intermediate for the research and development of novel therapeutic agents. This compound is primarily needed by R&D laboratories and manufacturers in the pharmaceutical and agrochemical sectors, where it serves as a key building block for synthesizing bioactive molecules.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
  • Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and hit-to-lead optimization for discovering new active pharmaceutical ingredients (APIs).
  • Agrochemical Development: Serves as a building block for creating novel pesticides, herbicides, or fungicides due to the bioactive nature of the quinazolinone core.
  • Biochemical Research: Employed as a standard or reagent in enzymatic assays and biochemical studies to investigate specific biological pathways.
  • Organic Synthesis: Utilized as a specialized synthon for constructing complex heterocyclic compounds in academic and industrial research settings.

Basic Information

Product Name 4(3H)-Quinazolinone, 2-(4-Chlorophenyl)-
CAS No. 7455-77-8
Molecular Formula C14H9ClN2O
Molecular Weight 256.69 g/mol
Synonyms 2-(4-Chlorophenyl)-4(3H)-quinazolinone; 2-(4-Chlorophenyl)quinazolin-4(3H)-one; 2-(p-Chlorophenyl)-4-hydroxyquinazoline; 2-(4-Chlorophenyl)-3,4-dihydro-4-oxoquinazoline; 4-Hydroxy-2-(4-chlorophenyl)quinazoline; NSC 403697; Quinazolin-4(3H)-one, 2-(4-chlorophenyl)-
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Quality Control

Our 4(3H)-Quinazolinone, 2-(4-Chlorophenyl)- is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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