Description

2-(2-Chloroethyl)-4-Methyl-1,3-Dioxolane is a versatile chlorinated dioxolane derivative, a key protected form of a chlorinated aldehyde or ketone. This compound is valued for its role as a reactive intermediate and protecting group in complex organic syntheses, offering chemists a handle for selective transformations. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a masked carbonyl or chlorinated side chain.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where its reactive chloroethyl group enables further functionalization.
• Polymer & Resin Modifier: Acts as a monomer or cross-linking agent in specialty polymer formulations to introduce specific chemical functionalities.
• Organic Synthesis Reagent: Serves as a versatile protecting group for aldehydes and ketones in multi-step synthetic routes, allowing for orthogonal deprotection strategies.
• Ligand & Catalyst Precursor: Utilized in the development of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Flavor & Fragrance Ingredient Synthesis: Employed in the controlled synthesis of complex aroma chemicals and flavor compounds.

Basic Information

Product Name	2-(2-Chloroethyl)-4-Methyl-1,3-Dioxolane
CAS No.	7451-06-1
Molecular Formula	C₆H₁₁ClO₂
Molecular Weight	150.60 g/mol
Synonyms	4-Methyl-2-(2-chloroethyl)-1,3-dioxolane; 2-(2-Chloroethyl)-4-methyl-1,3-dioxolane; 1,3-Dioxolane, 2-(2-chloroethyl)-4-methyl-; 4-Methyl-2-(β-chloroethyl)-1,3-dioxolane; 2-(β-Chloroethyl)-4-methyl-1,3-dioxolane; Chloroethyl methyl dioxolane; Acetaldehyde, chloro-, cyclic acetal with 1,2-propanediol
EINECS	231-245-8

Quality Control

Our 2-(2-Chloroethyl)-4-Methyl-1,3-Dioxolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. The container should be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.440 - 1.445
Density (g/mL at 20°C)	1.10 - 1.15

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.