Description

4-Hydroperoxy 2-Nonenal is a reactive lipid peroxidation product, specifically an alpha,β-unsaturated aldehyde bearing a hydroperoxy group. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a key mediator of oxidative stress and cellular signaling pathways. It is primarily utilized by researchers and manufacturers in the life sciences sector for studying inflammation, aging, and cytotoxicity mechanisms.

Application

• Biochemical Research: A critical standard and reagent for investigating lipid peroxidation, oxidative stress, and redox signaling in cellular models.
• Pharmaceutical Development: Used in studies targeting inflammatory diseases, neurodegenerative disorders, and metabolic syndromes where oxidative damage is a contributing factor.
• Toxicology Studies: Employed as a model electrophile to study cellular responses to reactive carbonyl species and the activation of protective pathways like the Nrf2/ARE system.
• Analytical Reference Standard: Serves as a high-purity calibrant in mass spectrometry (MS), high-performance liquid chromatography (HPLC), and other analytical techniques for quantifying lipid-derived aldehydes.
• Cosmeceutical Research: Applied in studies examining skin aging and the efficacy of antioxidants in neutralizing reactive lipid species.
• Food Science: Investigated for its role in the oxidative rancidity of lipids and the formation of flavor/aroma compounds in food products.

Basic Information

Product Name	4-Hydroperoxy 2-Nonenal
CAS No.	7439-43-2
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	4-HPNE; 4-Hydroperoxy-2-nonenal; 4-Hydroperoxy-trans-2-nonenal; 2-Nonenal, 4-hydroperoxy-; (E)-4-Hydroperoxynon-2-enal; Lipid peroxidation product 4-HPNE; 4-Hydroperoxy-trans-2-nonen-1-al; 4-Hydroperoxy-2E-nonenal
EINECS	Contact for details

Quality Control

Our 4-Hydroperoxy 2-Nonenal is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC purity analysis and spectroscopic identification (NMR, IR), to ensure high chemical integrity and lot-to-lot consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity, and stability.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at or below -20°C under an inert atmosphere (e.g., argon or nitrogen) to minimize decomposition. The material is easily oxidized and light-sensitive; allow it to reach ambient temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.