Description

Ethyl 2-Iodo-2-Methylpropionate is a versatile halogenated ester building block, primarily valued for its role as a key intermediate in organic synthesis. Its structure, featuring a reactive iodo group adjacent to a quaternary carbon, makes it a crucial reagent for introducing the tert-butyl moiety and for various carbon-carbon bond-forming reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing complex molecular scaffolds.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and plant growth regulators.
• Organic Synthesis Reagent: Employed in alkylation reactions, cross-coupling reactions (e.g., Negishi, Kumada), and as a precursor for generating tert-butyl radicals.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Chemical Research & Development: A valuable tool for academic and industrial R&D labs exploring new synthetic methodologies and reaction pathways.
• Fine Chemical Production: Integral to the multi-step synthesis of complex flavors, fragrances, and other high-value fine chemicals.

Basic Information

Product Name	Ethyl 2-Iodo-2-Methylpropionate
CAS No.	7425-55-0
Molecular Formula	C6H11IO2
Molecular Weight	242.06 g/mol
Synonyms	Ethyl α-Iodoisobutyrate; 2-Iodo-2-methylpropionic Acid Ethyl Ester; Ethyl 2-Iodo-2-methylpropanoate; Ethyl Iododimethylacetate; Iododimethylacetic Acid Ethyl Ester; Ethyl α-Iodo-α-methylpropionate; Ethyl Iodopivalate (less common)
EINECS	Contact for details

Quality Control

Our Ethyl 2-Iodo-2-Methylpropionate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by GC/HPLC and impurity profiling, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and specific test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Impurities (GC/HPLC)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.