Description

2-Bromocinnamic Acid is a versatile halogenated cinnamic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the reactive bromine substituent, which enables efficient cross-coupling reactions and further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a cinnamic acid scaffold.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents.
• Material Science Research: Employed as a monomer or building block for developing advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Acts as a versatile linker or probe in bioconjugation chemistry and activity-based protein profiling.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed coupling reactions to create complex biaryl structures.
• Academic & R&D: A fundamental reagent in university and corporate research laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	2-Bromocinnamic Acid
CAS No.	7345-79-1
Molecular Formula	C9H7BrO2
Molecular Weight	227.06 g/mol
Synonyms	(2-Bromophenyl)acrylic acid; 3-(2-Bromophenyl)-2-propenoic acid; 2-Bromocinnameic acid; (E)-3-(2-Bromophenyl)acrylic acid; trans-2-Bromocinnamic acid; α-Bromo-o-cinnamic acid; NSC 403697; o-Bromocinnamic acid
EINECS	Contact for details

Quality Control

Our 2-Bromocinnamic Acid is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	208 - 212 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.