Description

1,4-Dihydro-1,4-Ethanonaphthalene is a specialized bicyclic organic compound with a unique bridged structure, serving as a valuable intermediate in advanced chemical synthesis. Its rigid, fused-ring framework makes it a critical building block for creating complex molecular architectures in pharmaceutical and material science research. This compound is essential for R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and functional organic materials.

Application

• Pharmaceutical Intermediate: Key synthon in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring bridged or strained ring systems.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where its unique carbon skeleton can contribute to new modes of action.
• Material Science Precursor: Serves as a starting material for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions and other cycloadditions to construct polycyclic compounds in academic and industrial research laboratories.
• Catalyst Ligand Development: Potential framework for creating novel ligands used in asymmetric catalysis and transition metal complexes.
• Fine Chemical Manufacturing: Intermediate in the multi-step production of dyes, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	1,4-Dihydro-1,4-Ethanonaphthalene
CAS No.	7322-46-5
Molecular Formula	C₁₂H₁₂
Molecular Weight	156.23 g/mol
Synonyms	1,4-Ethanonaphthalene, 1,4-dihydro-; 1,4-Dihydro-1,4-ethanonaphthalene; Benzobarrelene; 1,4-Dihydrobenzocyclooctene; Bicyclo[4.2.2]deca-1,7,9-triene; 1,2,3,4-Tetrahydro-1,4-ethanonaphthalene; 1,4-Methano-1,4-dihydronaphthalene (incorrect but common alias)
EINECS	Contact for details

Quality Control

Every batch of 1,4-Dihydro-1,4-Ethanonaphthalene is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of research and process development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support applications requiring high-purity intermediates, including those under cGMP guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.