Description

5-Chloro-1,3-Benzodioxole is a versatile halogenated benzodioxole derivative, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in its unique fused-ring structure, which provides a reactive scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working in the synthesis of active pharmaceutical ingredients (APIs), specialty chemicals, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its halogenated aromatic core.
• Organic Synthesis Reagent: Acts as a versatile precursor for introducing the chlorobenzodioxole moiety into more complex molecular architectures via coupling and substitution reactions.
• Material Science Research: Investigated as a monomer or functional additive in the development of specialty polymers and advanced organic materials.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing certain aroma chemicals, subject to specific purity and regulatory compliance.

Basic Information

Product Name	5-Chloro-1,3-Benzodioxole
CAS No.	7228-38-8
Molecular Formula	C7H5ClO2
Molecular Weight	156.57 g/mol
Synonyms	5-Chlorobenzodioxole; 5-Chloro-1,3-benzodioxole; 5-Chloro-1,3-benzodioxol; 5-Chlorobenzo[d][1,3]dioxole; 1,3-Benzodioxole, 5-chloro-; 5-Chloro-2H-1,3-benzodioxole; 5-Chlorobenzo-1,3-dioxole
EINECS	Contact for details

Quality Control

Our 5-Chloro-1,3-Benzodioxole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay purity and impurity profiles. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.