Description

2-Fluoro-α-D-2-Deoxy-Glucose is a fluorinated glucose analog widely used as a key intermediate in radiopharmaceutical synthesis. This compound is essential for producing the positron emission tomography (PET) tracer [18F]FDG, a cornerstone of modern diagnostic imaging. It is primarily required by pharmaceutical manufacturers, radiochemistry research facilities, and diagnostic imaging centers for the development and production of critical medical diagnostics.

Application

• Radiopharmaceutical Synthesis: Primary precursor for the production of Fluorodeoxyglucose F 18 ([18F]FDG), the most widely used PET imaging agent.
• Oncology Diagnostics: Enables the manufacture of tracers for detecting, staging, and monitoring the treatment response of various cancers.
• Neurology and Cardiology Research: Used in developing PET tracers for studying brain metabolism, neurological disorders (e.g., Alzheimer's, epilepsy), and myocardial viability.
• Academic and Pharmaceutical R&D: Serves as a critical building block in research for novel diagnostic agents and drug discovery programs.
• GMP Manufacturing: Supplied under controlled conditions for use in Good Manufacturing Practice (GMP) compliant production of approved radiopharmaceuticals.
• Metabolic Studies: Acts as a tool compound in biochemical research to investigate glucose uptake and metabolic pathways in cells.

Basic Information

Product Name	2-Fluoro-α-D-2-Deoxy-Glucose
CAS No.	7226-39-3
Molecular Formula	C₆H₁₁FO₅
Molecular Weight	182.15 g/mol
Synonyms	2-Fluoro-2-deoxy-D-glucose; 2-FDG; FDG Precursor; 2-Fluoro-2-deoxy-α-D-glucopyranose; α-2-Fluoro-2-deoxy-D-glucose; 2-F-2-DG; 2-Deoxy-2-fluoro-D-glucose; Fluorodeoxyglucose precursor
EINECS	Contact for details

Quality Control

Our 2-Fluoro-α-D-2-Deoxy-Glucose is manufactured with a focus on high purity and consistency, critical for radiopharmaceutical applications. Quality is assured through rigorous analytical testing, including HPLC, NMR, and specific rotation analysis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Production can be aligned with GMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	[α]²⁰D: +40° to +44° (c=1 in H₂O)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.