Description

Dl-4-Hydroxymandelic Acid Monohydrate is a chiral organic compound belonging to the class of mandelic acid derivatives. This chemical is a valuable intermediate and building block in fine chemical synthesis, prized for its hydroxyl and carboxylic acid functional groups. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of various active pharmaceutical ingredients (APIs), particularly those targeting adrenergic systems.
• Agrochemical Synthesis: Used as a precursor in the development of advanced herbicides, fungicides, and plant growth regulators.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway analysis related to tyrosine and phenylalanine metabolism.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, including flavors, fragrances, and advanced materials.
• Asymmetric Synthesis: Acts as a starting material or resolving agent in chiral pool synthesis for creating enantiomerically pure compounds.

Basic Information

Product Name	Dl-4-Hydroxymandelic Acid Monohydrate
CAS No.	7198-10-9
Molecular Formula	C8H8O4 • H2O
Molecular Weight	186.16 g/mol (Anhydrous basis: 168.15 g/mol)
Synonyms	DL-4-Hydroxymandelic Acid Hydrate; (±)-4-Hydroxymandelic Acid Monohydrate; 2-Hydroxy-2-(4-hydroxyphenyl)acetic Acid Monohydrate; 4-Hydroxy-DL-mandelic Acid Hydrate; p-Hydroxymandelic Acid; HMA; (RS)-2-Hydroxy-2-(4-hydroxyphenyl)acetic Acid; 4-Hydroxyphenylglycolic Acid
EINECS	Contact for details

Quality Control

Our Dl-4-Hydroxymandelic Acid Monohydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, chiral purity, and impurity profiles. While typically supplied as a research-grade material, production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	8.0 - 10.0% (Theoretical for monohydrate: ~9.68%)
Melting Point	Approx. 120 - 125°C (decomposes)
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Optical Rotation	± 0.2° (c=1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.