Description

[(2R)-Oxolan-2-Yl]Methanamine Hydrochloride is a high-purity chiral amine salt, a key building block in advanced organic synthesis. Its defined stereochemistry and hydrochloride salt form offer enhanced stability and handling properties for precise chemical manufacturing. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and complex chiral molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Asymmetric Catalysis: Used as a precursor for chiral ligands and catalysts in enantioselective synthesis.
• Agrochemical Development: Serves as a building block for creating chiral active ingredients with improved efficacy and environmental profiles.
• Peptide Mimetics & Conjugates: Incorporated into peptide backbones to modify stability, bioavailability, and biological activity.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and medicinal chemistry projects.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals requiring high stereochemical purity.

Basic Information

Product Name	[(2R)-Oxolan-2-Yl]Methanamine Hydrochloride
CAS No.	7175-80-6
Molecular Formula	C5H12ClNO
Molecular Weight	137.61 g/mol
Synonyms	(R)-2-(Aminomethyl)tetrahydrofuran Hydrochloride; (R)-Tetrahydrofurfurylamine Hydrochloride; (R)-THFA Hydrochloride; (2R)-2-(Aminomethyl)oxolane Hydrochloride; (R)-Aminomethyltetrahydrofuran HCl; (R)-Oxolan-2-ylmethanamine Hydrochloride; (R)-2-Tetrahydrofurylmethylamine Hydrochloride
EINECS	Contact for details

Quality Control

Our [(2R)-Oxolan-2-Yl]Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.