Description

4,8-Dichloro-Quinazoline is a versatile and high-value halogenated heterocyclic building block, essential for advanced organic synthesis. Its molecular structure, featuring two reactive chlorine atoms at the 4 and 8 positions, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the quinazoline core's bioactivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as charge-transport layers or luminescent compounds.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and affinity tags for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring functionalized quinazoline derivatives.

Basic Information

Product Name	4,8-Dichloro-Quinazoline
CAS No.	7148-34-7
Molecular Formula	C8H4Cl2N2
Molecular Weight	199.04 g/mol
Synonyms	4,8-Dichloroquinazoline; Quinazoline, 4,8-dichloro-; 4,8-Dichloro-1,3-diazanaphthalene; 4,8-Dichloroquinazoline; 4,8-Dichloro-benzo[d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4,8-Dichloro-Quinazoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.