Description

Methyl D-Valinate Hydrochloride is a high-purity chiral building block and protected amino acid derivative essential for advanced organic synthesis. Its primary value lies in providing a stereochemically defined valine unit for the construction of complex peptides, peptidomimetics, and active pharmaceutical ingredients (APIs). This product is critically needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic agents, and specialty fine chemicals where precise chirality control is paramount.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of peptide-based drugs and protease inhibitors.
• Peptide Chemistry: Used as a protected D-valine derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material for the preparation of non-natural amino acids and complex organic molecules.
• Biochemical Research: Employed in studies of enzyme specificity, metabolic pathways, and structure-activity relationships (SAR).
• Agrochemical Development: Potential intermediate for creating chiral active ingredients with specific biological activity.
• Material Science: Building block for specialty polymers and dendrimers with tailored properties.

Basic Information

Product Name	Methyl D-Valinate Hydrochloride
CAS No.	7146-15-8
Molecular Formula	C6H14ClNO2
Molecular Weight	167.63 g/mol
Synonyms	D-Valine, methyl ester, hydrochloride; Methyl (R)-2-amino-3-methylbutanoate hydrochloride; (R)-2-Amino-3-methylbutyric acid methyl ester hydrochloride; Methyl D-valine HCl; D-Val-OMe·HCl; (R)-Methyl 2-amino-3-methylbutanoate hydrochloride; Methyl (R)-valinate hydrochloride; D-Valine methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl D-Valinate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting standards for research and cGMP-grade applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.