Description

8-Cyano-4-Oxo-1,4-Dihydro-Quinoline-2-Carboxylic Acid Methyl Ester is a high-purity, versatile quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for its role in creating complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinolone-based antibiotics and other therapeutic agents targeting bacterial infections.
• Agrochemical Research: Used in developing new fungicides and herbicides, leveraging the bioactive quinoline core for crop protection.
• Material Science: Serves as a building block for organic semiconductors, light-emitting diodes (OLEDs), and other functional electronic materials.
• Chemical Synthesis: An important reagent for constructing complex heterocyclic frameworks in medicinal and combinatorial chemistry.
• Dye & Pigment Industry: Utilized in the synthesis of advanced colorants and fluorescent markers due to its conjugated system.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry and drug discovery programs.

Basic Information

Product Name	8-Cyano-4-Oxo-1,4-Dihydro-Quinoline-2-Carboxylic Acid Methyl Ester
CAS No.	7101-83-9
Molecular Formula	C₁₂H₈N₂O₃
Molecular Weight	228.21 g/mol
Synonyms	Methyl 8-cyano-4-oxo-1,4-dihydroquinoline-2-carboxylate; 8-Cyano-1,4-dihydro-4-oxo-2-quinolinecarboxylic Acid Methyl Ester; 2-Quinolinecarboxylic acid, 8-cyano-1,4-dihydro-4-oxo-, methyl ester; Methyl 8-cyano-1,4-dihydro-4-oxoquinoline-2-carboxylate; 8-Cyano-4-oxo-1H-quinoline-2-carboxylic acid methyl ester; 7101-83-9; Quinoline-2-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 8-Cyano-4-Oxo-1,4-Dihydro-Quinoline-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider conditions under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.