Description

(R)-3-(Pyrrolidin-2-Yl)Pyridine is a chiral, nitrogen-containing heterocyclic compound that serves as a critical building block in modern organic synthesis. Its value lies in its unique stereochemistry and bifunctional structure, making it an essential intermediate for creating complex molecules with specific biological activity. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs), particularly in therapeutic areas like neurology and oncology.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially nicotinic receptor ligands and other central nervous system (CNS) active compounds.
• Asymmetric Catalyst Ligand Precursor: Used to develop chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity in industrial chemical processes.
• Agrochemical Research: Serves as a building block for creating new, more selective pesticides and herbicides with improved environmental profiles.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways and protein function.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(R)-3-(Pyrrolidin-2-Yl)Pyridine
CAS No.	7076-23-5
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	(R)-2-(3-Pyridyl)pyrrolidine; (R)-3-(2-Pyrrolidinyl)pyridine; (R)-Nicotine Intermediate; (R)-Pyrrolidin-2-yl-pyridine; (R)-P2P; (R)-3-Pyridylpyrrolidine; (R)-3-Pyrrolidin-2-ylpyridine; (2R)-3-(Pyrrolidin-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our production of (R)-3-(Pyrrolidin-2-Yl)Pyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We implement in-process controls and final release testing according to cGMP principles where applicable, ensuring the material meets the exacting standards required for advanced pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.