Description

2-Cyclopropyl-6-Fluoroquinoline-4-Carboxylic Acid CAS NO 784-58-7 is a high-purity, advanced pharmaceutical intermediate belonging to the fluoroquinolone class of compounds. This compound serves as a critical building block in the synthesis of next-generation antibacterial agents, offering significant value in the development of novel therapeutics. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract development and manufacturing organizations (CDMOs) engaged in antibiotic production.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel fluoroquinolone antibiotics.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the manufacturing process of potent antibacterial agents targeting resistant bacterial strains.
• Research & Development: Essential for medicinal chemistry programs focused on structure-activity relationship (SAR) studies to optimize antibacterial efficacy and safety profiles.
• Fine Chemical Production: Serves as a specialized building block for creating complex, high-value molecules in custom synthesis projects.
• Contract Manufacturing: Supplied to CDMOs for scale-up and commercial production of antibiotic formulations under GMP conditions.

Basic Information

Product Name	2-Cyclopropyl-6-Fluoroquinoline-4-Carboxylic Acid
CAS No.	784-58-7
Molecular Formula	C₁₃H₁₀FNO₂
Molecular Weight	231.22 g/mol
Synonyms	6-Fluoro-2-cyclopropylquinoline-4-carboxylic acid; 2-Cyclopropyl-6-fluoro-4-quinolinecarboxylic acid; 4-Quinolinecarboxylic acid, 2-cyclopropyl-6-fluoro-; 6-Fluoro-2-cyclopropyl-4-quinolinecarboxylic acid; 2-Cyclopropyl-6-fluoroquinoline-4-carboxylate; 784-58-7 (CAS); 6-Fluoro-2-cyclopropylquinoline-4-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Cyclopropyl-6-Fluoroquinoline-4-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is supplied with each shipment, and we can support customer audits and regulatory filings as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.