Description

(2-Amino-5-Chlorophenyl)(4-Fluorophenyl)Methanone is a high-purity, bifunctional aromatic ketone building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an amino and a halogenated aromatic system, makes it a versatile intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential kinase inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Material Science: Serves as a building block for specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a scaffold for further functionalization.
• Academic & Contract Research: Essential for medicinal chemistry programs and process development in academic and contract research organizations (CROs).

Basic Information

Product Name	(2-Amino-5-Chlorophenyl)(4-Fluorophenyl)Methanone
CAS No.	784-40-7
Molecular Formula	C13H9ClFNO
Molecular Weight	249.67 g/mol
Synonyms	2-Amino-5-chloro-4'-fluorobenzophenone; 2'-Amino-5'-chloro-4-fluorobenzophenone; 4-Fluoro-2-amino-5-chlorobenzophenone; (2-Amino-5-chlorophenyl)(4-fluorophenyl)methanone; 5-Chloro-2-amino-4'-fluorobenzophenone; 784-40-7; Methanone, (2-amino-5-chlorophenyl)(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of (2-Amino-5-Chlorophenyl)(4-Fluorophenyl)Methanone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container to maintain purity.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.