Description

3,4-Dihydroxymandelic Acid is a significant catecholamine metabolite and a valuable synthetic intermediate in organic chemistry. Its chemical structure makes it a key precursor for the synthesis of complex molecules, including certain pharmaceuticals and fine chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, biochemical, and life science sectors who require high-purity intermediates for drug development and metabolic studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular systems.
• Biochemical Research: Used as a standard or reagent in metabolic pathway studies, especially related to catecholamine (e.g., dopamine, norepinephrine) metabolism and oxidative stress.
• Fine Chemical Synthesis: Serves as a versatile chiral synthon for producing complex organic compounds, flavors, and fragrances.
• Analytical Reference Standard: Employed in clinical and diagnostic laboratories for calibrating equipment and validating methods in HPLC, LC-MS, or other analytical techniques.
• Enzymology Studies: Acts as a substrate or inhibitor in enzymatic assays to study the activity of enzymes like catechol-O-methyltransferase (COMT).

Basic Information

Product Name	3,4-Dihydroxymandelic Acid
CAS No.	775-01-9
Molecular Formula	C8H8O5
Molecular Weight	184.15 g/mol
Synonyms	DHMA; 3,4-Dihydroxymandelic Acid; 2-Hydroxy-2-(3,4-dihydroxyphenyl)acetic Acid; 3,4-Dihydroxyphenylglycolic Acid; 3,4-Dihydroxybenzene glycolic Acid; DOMA; (3,4-Dihydroxyphenyl)(hydroxy)acetic Acid
EINECS	212-277-4

Quality Control

Our 3,4-Dihydroxymandelic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle the material under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.