Description

2-Hydroxy-5-Nitrobenzyl Bromide is a versatile brominated aromatic compound that serves as a key intermediate in advanced organic synthesis. Its reactive bromine atom and phenolic hydroxyl group make it a valuable building block for constructing complex molecules with specific functionalities. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a nitrophenol or bromobenzene scaffold.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and other crop protection agents where its nitro and bromo groups enable specific biological activity.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing azo dyes and other complex colorants, leveraging its nitro and hydroxyl functional groups.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic structure and reactivity.
• Bioconjugation and Proteomics: Useful as a modifying agent for tryptophan residues in peptides and proteins for analytical and research purposes.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions like Suzuki or Heck couplings to form biaryl structures.

Basic Information

Product Name	2-Hydroxy-5-Nitrobenzyl Bromide
CAS No.	772-33-8
Molecular Formula	C7H6BrNO3
Molecular Weight	232.03 g/mol
Synonyms	5-Nitro-2-hydroxybenzyl Bromide; 2-Bromomethyl-4-nitrophenol; (5-Nitro-2-hydroxyphenyl)methyl Bromide; 4-Nitro-2-hydroxybenzyl Bromide; 2-Hydroxy-5-nitrobenzyl Bromide; 2-Hydroxy-5-nitrobenzylbromide; 2-Hydroxy-5-nitrobenzyl bromide; 2-Hydroxy-5-nitrobenzylbromide
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-5-Nitrobenzyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light and moisture to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.