Description

4-Ethynylanisole is a versatile aromatic alkyne building block, also known as 4-Ethynylmethoxybenzene. This compound is valued for its terminal alkyne functionality, which enables efficient cross-coupling reactions like the Sonogashira reaction, making it a critical intermediate in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring conjugated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers, conductive materials, and advanced resins.
• Liquid Crystal & OLED Materials: A precursor in the synthesis of organic electronic materials for displays and lighting applications.
• Chemical Research & Development: Essential reagent in academic and industrial labs for methodology development and creating molecular libraries.
• Coordination Chemistry & Catalyst Ligand: The ethynyl group can act as a ligand or be modified to create complexing agents for metal catalysts.

Basic Information

Product Name	4-Ethynylanisole
CAS No.	768-60-5
Molecular Formula	C9H8O
Molecular Weight	132.16 g/mol
Synonyms	1-Ethynyl-4-methoxybenzene; 4-Methoxyphenylacetylene; p-Methoxyphenylacetylene; 4-Ethynylmethoxybenzene; 4-Methoxybenzeneacetylene; (4-Methoxyphenyl)ethyne; p-Ethynylanisole; Anisole, 4-ethynyl-
EINECS	212-200-1

Quality Control

Our 4-Ethynylanisole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for manufacturing, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to prevent potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.