Description

2-Chloroanisole is a versatile aromatic ether and a key halogenated intermediate in advanced organic synthesis. Its unique structure, featuring both an electron-donating methoxy group and an electron-withdrawing chlorine atom, makes it a valuable building block for creating complex molecules. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise chemical functionality is required.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a substituted anisole moiety.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and pesticides, where its chloroanisole structure acts as a core scaffold.
• Dye and Pigment Manufacturing: Functions as an intermediate in the production of complex organic dyes and pigments, contributing to color fastness and specific hue properties.
• Liquid Crystal Materials: Employed in the synthesis of advanced materials for electronic displays due to its stable aromatic system and modifiable functional groups.
• Fragrance and Flavor Chemistry: Acts as a starting material or modifying agent in the creation of specific aromatic compounds, though typically in highly purified grades.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions (e.g., Suzuki, Heck) and as a protecting group or directing group in complex multi-step syntheses.

Basic Information

Product Name	2-Chloroanisole
CAS No.	766-51-8
Molecular Formula	C7H7ClO
Molecular Weight	142.58 g/mol
Synonyms	1-Chloro-2-methoxybenzene; o-Chloroanisole; 2-Methoxychlorobenzene; 2-Chloromethoxybenzene; o-Methoxychlorobenzene; 2-Chlorophenyl methyl ether; Methyl 2-chlorophenyl ether
EINECS	212-165-2

Quality Control

Our 2-Chloroanisole is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	1.18 - 1.22 g/mL
Refractive Index (n20D)	1.540 - 1.545

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.