Description

6-Aza-Spiro[3.4]Octane is a versatile and highly valuable nitrogen-containing spirocyclic building block in organic synthesis. Its unique bridged bicyclic structure makes it a critical intermediate for constructing complex molecular architectures with potential biological activity. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key scaffold for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Building Block: Used to introduce conformational constraint and three-dimensionality into drug candidates, potentially improving selectivity and metabolic stability.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Development: Utilized to create tool compounds for studying enzyme function and biological pathways.
• Ligand Synthesis for Catalysis: Acts as a backbone for constructing sophisticated chiral ligands used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or precursor for novel polymers with specific thermal or mechanical properties.

Basic Information

Product Name	6-Aza-Spiro[3.4]Octane
CAS No.	765-64-0
Molecular Formula	C7H13N
Molecular Weight	111.18 g/mol
Synonyms	6-Azaspiro[3.4]octane; 1-Azaspiro[3.4]octane; Hexahydro-1H-pyrrolo[3,4-c]pyrrole; 1H-Pyrrolo[3,4-c]pyrrole, hexahydro-; 6-Aza-spiro[3.4]octane; Azaspirooctane; Spirocyclic amine building block
EINECS	Contact for details

Quality Control

Our 6-Aza-Spiro[3.4]Octane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.