Description

n-tert-Butylacetamide (CAS NO 762-84-5) is a specialized organic compound serving as a versatile building block and intermediate in advanced chemical synthesis. Its unique sterically hindered structure, featuring the tert-butyl group adjacent to the amide functionality, makes it valuable for modulating reactivity and introducing bulky substituents in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and performance materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those requiring sterically hindered amide motifs for enhanced metabolic stability or target binding.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the tert-butylacetamide moiety contributes to specific biological activity and environmental persistence profiles.
• Organic Synthesis Reagent: Acts as a protected amine equivalent or a precursor for introducing the tert-butyl group into complex molecular architectures in research and development.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed in the creation of specialty polymers and resins, where it can be incorporated to alter thermal properties, solubility, or mechanical strength.
• Chemical Research: A valuable reference standard and reagent in academic and industrial laboratories for studying amide chemistry and steric effects.

Basic Information

Product Name	n-tert-Butylacetamide
CAS No.	762-84-5
Molecular Formula	C6H13NO
Molecular Weight	115.17 g/mol
Synonyms	N-(1,1-Dimethylethyl)acetamide; N-tert-Butylacetamide; Acetamide, N-(1,1-dimethylethyl)-; 2-Methyl-2-propanamine, N-acetyl-; t-Butylacetamide; tert-Butylacetamide; N-Acetyl-tert-butylamine; N-(tert-Butyl)acetamide
EINECS	212-109-6

Quality Control

Our n-tert-Butylacetamide is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing specific results for purity, residual solvents, and other critical parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	78°C - 82°C
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.