Description

Methylphosphonic Chloride Fluoride is a highly reactive organophosphorus compound that serves as a critical building block in advanced chemical synthesis. Its bifunctional nature, featuring both chloride and fluoride leaving groups, makes it an exceptionally versatile reagent for introducing the methylphosphonate moiety. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to create novel active ingredients, including nerve agent antidotes and specialized pesticides.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of bisphosphonate drugs and other bioactive molecules targeting bone disorders.
• Agrochemical Synthesis: Building block for creating organophosphate and phosphonate-based herbicides, insecticides, and plant growth regulators.
• Chemical Warfare Agent Simulant: Used in defensive research and development for the detection and decontamination of nerve agents.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized phosphonate ligands used in coordination chemistry and catalysis.
• Flame Retardant Research: Intermediate in the development of novel phosphorus-containing flame retardant additives for polymers.
• Material Science: Used in the surface modification of materials and the creation of metal-organic frameworks (MOFs) with specific properties.

Basic Information

Product Name	Methylphosphonic Chloride Fluoride
CAS No.	753-71-9
Molecular Formula	CH3ClFO2P
Molecular Weight	132.46 g/mol
Synonyms	Methylphosphonochloridofluoridate; Fluoromethylphosphonic Dichloride (common misnomer); Methylphosphonofluoridic Chloride; CH3P(O)FCl; Methylphosphonic Difluoride Chloride analog; Phosphonic acid, methyl-, chloride fluoride; Methylphosphonoyl Fluoride Chloride
EINECS	212-041-8

Quality Control

Every batch of Methylphosphonic Chloride Fluoride is produced and tested under stringent quality management protocols to ensure consistency and purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity and impurity profiles. Our quality system is designed to support cGMP and ISO standards for advanced intermediates, ensuring traceability and reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is highly volatile and hygroscopic (moisture-sensitive). It must be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from strong bases and oxidizers. Use appropriate corrosion-resistant storage equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.5 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.