Description

5-Bromo-2-Iodobenzoic Acid is a high-purity halogenated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and iodine substituents, makes it a versatile intermediate for constructing complex molecules with precise electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially in medicinal chemistry for creating libraries of bioactive compounds.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where halogenated aromatic rings are common structural motifs.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings due to its reactive halogen atoms.
• Ligand and Catalyst Development: Utilized to synthesize complex chelating ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Chemical Biology Probes: Acts as a starting material for creating labeled compounds and molecular probes for biochemical research.

Basic Information

Product Name	5-Bromo-2-Iodobenzoic Acid
CAS No.	740-00-1
Molecular Formula	C7H4BrIO2
Molecular Weight	326.91 g/mol
Synonyms	2-Iodo-5-bromobenzoic Acid; Benzoic acid, 5-bromo-2-iodo-; 5-Bromo-2-iodobenzoic acid; 740-00-1; 2-Iodo-5-bromobenzoic acid; NSC 403119; AI3-52732; BRN 2127615
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Iodobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from incompatible materials such as strong bases and oxidizing agents. Handle in accordance with good industrial hygiene and safety practice.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	205 - 210 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.