Description

7-Fluoro-1,2,3,4-Tetrahydro-Acridine-9-Carboxylic Acid is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceutical agents and functional materials, where its unique acridine scaffold and fluorine substituent impart specific biological and physicochemical properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new molecular entities.

Application

This versatile fluorinated intermediate is utilized in several high-value research and development applications:

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the bioactivity of the acridine core.
• Material Science Precursor: Employed in the synthesis of organic semiconductors, dyes, and fluorescent markers due to its conjugated ring system.
• Chemical Biology Probes: Acts as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring novel heterocyclic chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	7-Fluoro-1,2,3,4-Tetrahydro-Acridine-9-Carboxylic Acid
CAS No.	727-74-2
Molecular Formula	C14H12FNO2
Molecular Weight	245.25 g/mol
Synonyms	9H-Acridine-9-carboxylic acid, 1,2,3,4-tetrahydro-7-fluoro-; 7-Fluoro-1,2,3,4-tetrahydroacridine-9-carboxylic acid; 7-Fluoro-9-carboxy-1,2,3,4-tetrahydroacridine; 7-Fluoro-THAC; FTAC; 7-Fluoro-1,2,3,4-tetrahydro-9-acridinecarboxylic acid; 7-Fluoro-9H-acridine-9-carboxylic acid, 1,2,3,4-tetrahydro-
EINECS	Contact for details

Quality Control

Our 7-Fluoro-1,2,3,4-Tetrahydro-Acridine-9-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high standards, such as pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.