Description

Diethyl[2-(Benzyloxy)Ethyl]Phosphonate, 98 % is a high-purity organophosphorus compound that serves as a versatile and critical building block in advanced organic synthesis. Its primary value lies in its role as a key reagent for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient and stereoselective construction of carbon-carbon double bonds. This phosphonate ester is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise intermediates for developing active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, including antiviral and anticancer agents, via olefination reactions.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific alkene geometries are required for biological activity.
• Fine Chemical Manufacturing: Employed as a specialized reagent for constructing complex organic frameworks in flavors, fragrances, and functional materials.
• Academic & Industrial R&D: A staple reagent in research laboratories for method development and the exploration of new synthetic pathways involving phosphonate chemistry.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing phosphorus-containing ligands used in metal-catalyzed transformations.

Basic Information

Product Name	Diethyl[2-(Benzyloxy)Ethyl]Phosphonate, 98 %
CAS No.	727-18-4
Molecular Formula	C₁₃H₂₁O₄P
Molecular Weight	272.28 g/mol
Synonyms	Diethyl (2-Benzyloxyethyl)phosphonate; (2-Benzyloxyethyl)phosphonic Acid Diethyl Ester; Diethyl P-(2-Benzyloxyethyl)phosphonate; Benzyl 2-(Diethoxyphosphoryl)ethyl Ether; Phosphonic Acid, P-[2-(Phenylmethoxy)ethyl]-, Diethyl Ester; EINECS 211-979-8
EINECS	211-979-8

Quality Control

Our Diethyl[2-(Benzyloxy)Ethyl]Phosphonate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure it meets the specified 98% minimum purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0 %
Water Content (KF)	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.