Description

α,β-Dibromocinnamic Acid CAS NO 708-81-6 is a versatile brominated aromatic acid derivative, primarily valued as a key synthetic intermediate in organic chemistry. Its unique structure, featuring two bromine atoms on the alpha and beta carbons of the cinnamic acid backbone, makes it a crucial building block for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for coupling reactions, cyclizations, and the synthesis of bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for creating complex heterocycles and brominated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, where the bromine atoms serve as handles for further functionalization.
• Organic Synthesis Building Block: Employed in Heck-type coupling reactions, cycloadditions, and as a substrate for studying elimination and substitution mechanisms in organic chemistry.
• Material Science Research: Serves as a monomer or precursor for synthesizing specialized polymers and liquid crystalline materials with unique optical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and molecular tags for studying biological systems.
• Academic & Industrial R&D: A fundamental reagent for method development and discovery chemistry in university and corporate research laboratories.

Basic Information

Product Name	α,β-Dibromocinnamic Acid
CAS No.	708-81-6
Molecular Formula	C9H6Br2O2
Molecular Weight	305.95 g/mol
Synonyms	(E)-2,3-Dibromo-3-phenylacrylic acid; 2,3-Dibromocinnamic acid; alpha,β-Dibromohydrocinnamic acid; trans-α,β-Dibromocinnamic acid; (E)-α,β-Dibromocinnamic acid; 3-Phenyl-2,3-dibromoprop-2-enoic acid; NSC 404087
EINECS	211-913-8

Quality Control

Our α,β-Dibromocinnamic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation by FT-IR and NMR, and residual solvent analysis. Certificates of Analysis (COA) are available for every batch and supplied upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.