Description

1-Cyclopropyl-1-(4-Fluorophenyl)Methanamine is a versatile chiral amine building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a cyclopropyl and a fluorinated aromatic ring, makes it a critical intermediate for constructing complex molecules with tailored biological and physical properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the research and synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing new pesticides and herbicides, where the fluorine atom and cyclopropyl group can enhance metabolic stability and biological activity.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty monomers and advanced polymers with specific optical or electronic properties.
• Chemical Biology Probes: Acts as a scaffold for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	1-Cyclopropyl-1-(4-Fluorophenyl)Methanamine
CAS No.	705-14-6
Molecular Formula	C10H12FN
Molecular Weight	165.21 g/mol
Synonyms	(4-Fluorophenyl)(cyclopropyl)methanamine; α-Cyclopropyl-4-fluoro-benzenemethanamine; 1-(4-Fluorophenyl)-1-cyclopropylmethanamine; 1-Cyclopropyl-1-(4-fluorophenyl)methylamine; Benzenemethanamine, α-cyclopropyl-4-fluoro-; (Cyclopropyl)(4-fluorophenyl)methanamine; 4-Fluoro-α-cyclopropylbenzylamine
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-1-(4-Fluorophenyl)Methanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.