Description

Phenyl Trifluoromethyl Sulphoxide is a versatile organosulfur compound featuring a trifluoromethylsulfinyl group attached to a phenyl ring. This unique structure makes it a valuable building block and intermediate in advanced organic synthesis, particularly for introducing fluorinated motifs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to create novel molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated sulfoxide or sulfone moieties for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of modern pesticides and herbicides, where the trifluoromethyl group can enhance lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral sulfoxide ligands used in asymmetric catalysis.
• Material Science Research: Employed in the synthesis of advanced polymers and functional materials with specific electronic or surface properties.
• Organic Synthesis Building Block: A reactive intermediate for constructing complex molecules via reactions such as nucleophilic additions or cross-couplings at the sulfinyl center.

Basic Information

Product Name	Phenyl Trifluoromethyl Sulphoxide
CAS No.	703-18-4
Molecular Formula	C7H5F3OS
Molecular Weight	194.17 g/mol
Synonyms	(Trifluoromethylsulfinyl)benzene; α,α,α-Trifluorothioanisole S-oxide; Benzene, (trifluoromethylsulfinyl)-; Phenyl(trifluoromethyl)sulfoxide; Trifluoromethyl phenyl sulfoxide
EINECS	Contact for details

Quality Control

Our Phenyl Trifluoromethyl Sulphoxide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.